X. Treatment of hypertension in association with nondiabetic chronic kidney disease

Prevention and Treatment

Recommendations

  1. For patients with hypertension and proteinuric chronic kidney disease (urinary protein level > 150 mg in 24 hours or albumin to creatinine ratio > 30 mg/mmol), initial therapy should be with an ACE inhibitor (Grade A) or an ARB (Grade B; revised recommendation).
  2. In most cases, combination therapy with other antihyper-tensive agents might be needed to reach target BP levels (Grade D).
  3. The combination of an ACE inhibitor and ARB is not recommended for patients with chronic kidney disease (Grade B; revised recommendation).