X. Treatment of hypertension in association with nondiabetic chronic kidney disease
PREVENTION AND TREATMENT
- For patients with hypertension and proteinuric chronic kidney disease (urinary protein level > 150 mg in 24 hours or albumin to creatinine ratio > 30 mg/mmol), initial therapy should be with an ACE inhibitor (Grade A) or an ARB (Grade B; revised recommendation).
- In most cases, combination therapy with other antihyper-tensive agents might be needed to reach target BP levels (Grade D).
- The combination of an ACE inhibitor and ARB is not recommended for patients with chronic kidney disease (Grade B; revised recommendation).